Apart from adding aroma and orange tinge to food, paprika also manifest certain ill effects on health. One of the most probable side effects of paprika is allergy. People who experience sensitivity towards pepper or ball pepper are known to show similar symptoms with paprika powder. You should practice caution before consuming paprika in excess as it can wreck havoc on your gastrointestinal health. The story does not end here, paprika powder hinders the cancer and Alzheimer's disease drug delivery process in cells and tissues. It also affects the working route of pain killers and antibiotics.